1977年，美国俄亥俄州连续强暴案嫌犯比利‧米利根被警方逮捕，但是他对自己犯下的罪行居然毫无记忆。事实上，在他体内总共有24个人格存在，这些人格不仅在性格上，甚至连智商、年龄、国籍、语言、性别等方面也都不尽相同。这些不可思议的人格，到底是如何产生的呢？他到底是个欺骗公众的骗子，或只是个不幸的受害者？
父亲自杀，继父百般虐待，这让比利一方面迫切地渴望逃避这个世界──多次自杀，另一方面求生的本能又来安慰、保护自己，这两种力量纽结在一起，将比利撕成碎片……
当比利闭上眼睛，会有守护者里根出来击退施虐者，会有8岁的承受者戴维哭泣，女同性恋阿达拉娜、流氓菲利普、职业骗子凯文、小丑利伊、工作狂马克……像是一个队伍，每个人承担不同任务
一个人格来承受我的痛苦
一个人格来表现我的快乐
一个人格来保护我的身体
一个人格来享受他人的关爱
一个人格来学习逃脱
……
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